Atomic Force Microscopy

Optical Tweezers

Optical Trapping

Cellular Adhesion and Cytomechanics

Nano Life-Science

Lasing, S.A. provides JPK, leading manufacturer of nano-analytical instruments- particularly based on atomic force microscope (AFM) and optical tweezers systems- for life sciences and soft matter applications:


The NanoWizard® 4 BioScience AFM combines atomic resolution and fast scanning with line rates up to 70Hz in a system with a large scan range of 100µm. It is designed for highest mechanical and thermal stability on an inverted microscope for long term experiments, even on living cells. It has the lowest noise level for all AFM components such as the closed-loop scanner and deflection detection system. The electronics ensure the highest quality data.


CellHesion® products quantify single cell-cell and cell-surface interactions under physiological conditions.measures the interaction forces between a living cell bound to a cantilever and a target cell, functionalized substrate or biomaterial parallel, cytomechanical characteristics including stiffness and elasticity can be determined.


Nano Tracker 2 Force-Sensing Optical Tweezers and Optical Trapping. Optical tweezers platform based on research-grade inverted optical microscopes and designed for sensitive manipulation, force and tracking experiments.


Lasing, S.A. provides NANOLANE, company specialized in optical solutions at nanoscale and commercializes characterization tools based on the label-free patented SEEC (Surface Enhanced Ellipsometry Contrast) optical technique which extends the analysis possibilities of optical systems in the field of nanotechnologies. The products are suitable for characterization in the following topics: Life Sciences, Materials, nano-objects...


SEEC Microscopy: the only one to provide the visualization and the mapping of nanometric samples in air and in water:

  1. • in real-time

  2. • without any labeling

  3. • with a sub-micrometric lateral resolution (<300nm)

Vídeo: BioMat for the study of opaque samples combining optical microscopy with AFM

Vídeo: Tip-scanning AFM such as the NanoWizard® from JPK Instruments truly enables simultaneous AFM and optical microscopy measurements.

Automated Force Spectroscopy

Vídeo: Manipulation of a single DNA molecule using the two optical traps provided by JPK’s NanoTracker optical tweezers platform

Vídeo: Sarfus HR Station by Nanolane

Find out the key SEEC Equipment: Sarfus HR, ideal tool for label-free and real-time characterization of samples down to nanoscale. Sarfus HR not only tracks changes at surface but also provides high-resolution Imaging and directe quantitative data analysis.

Products

Applications

  1. • Combining fluorescence and atomic force microscopy

  2. • Piezoresponse Force Microscopy

  3. • Structural investigation of single bio-molecules

  4. • Determining the elastic modulus of biological samples using the atomic force microscope

  5. • Characterization of Graphene with the NanoWizard® 3 AFM

  6. • Single molecule force spectroscopy with the ForceRobot® 300

  7. • Quantifying cell-virus interactions using NanoTracker™ optical tweezers

  8. • Characterizing quantitative measurements of force and displacement with optical tweezers on the NanoTracker™

  9. • SARFUS : Study of chemical micropatterning on polycarbonate for peptide immobilization

  10. • SARFUS : Characterization of adhesive nanometric layer on SiO2 surface

SEEC Stations